I doubt that I would create two types of module in this shape, keeping the existing designs up to date is enough work without extra variants. It would also cost twice via JLCPCB as they charge you per PCB type.
I could easily add a fuse on the positive line on this PCB as there is plenty of room, you shouldn’t need one on the comms cables as these are already opto isolated.
Thermally these should be better than the existing 4.21 design as they are larger and have more copper to use as a heat sink, but you will need that with the higher balance current.